Advancing ICSI Robotics: Follow-Up on the Transition from Remote to Fully Automated Intracytoplasmic Sperm Injection

Conference Papers
Written By C22 Admin

Mendizabal-Ruiz et al., 2025

Intracytoplasmic sperm injection (ICSI), where a single sperm is injected directly into an egg, requires manual skill and years of training. The procedure's success varies between embryologists.

This study presents the first fully automated, AI-driven system that can perform all steps of ICSI. The system integrates computer vision, artificial intelligence, and precision mechanics to execute sperm selection, immobilization, egg positioning, and injection automatically, with human operators maintaining supervisory control.

Clinical testing with six patients showed the automated system achieved fertilization and embryo development rates statistically identical to manual ICSI, while completing most procedural steps autonomously. Three ongoing pregnancies from embryos created by the automated system demonstrate its clinical viability, representing a pivotal advancement in reproductive medicine automation.

The technology promises to standardize ICSI procedures globally, potentially making high-quality fertility treatments accessible in regions lacking specialized embryologists.

 
C22 Admin
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Pre-Clinical Validation of an AI-Powered Automated Robotic Intracytoplasmic Sperm Injection System
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