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Overview of automated systems for sperm preparation. (A) Pearl 1 system for swim-up (SU) featuring automated pipetting of semen and culture media, and completion of a sperm preparation procedure in a standard 15 ml conical tube. (B) Pearl 1 system for dish-based horizontal swim-out (HSO) sperm preparation featuring six-axis robotic arm, and dedicated semen cup and dish holder. (C) The HSO system autonomously produced the correct configuration of droplets to support sperm preparation by HSO. In this prototype, a human operator dispensed the oil overlay in the dish. Figure 1. Overview of automated systems for sperm preparation. (A) Pearl 1 system for swim-up (SU) featuring automated pipetting of semen and culture media, and completion of a sperm preparation procedure in a standard 15 ml conical tube. (B) Pearl 1 system for dish-based horizontal swim-out (HSO) sperm preparation featuring six-axis robotic arm, and dedicated semen cup and dish holder. (C) The HSO system autonomously produced the correct configuration of droplets to support sperm preparation by HSO. In this prototype, a human operator dispensed the oil overlay in the dish. https://images.squarespace-cdn.com/content/v1/67b94584cb4968452d57305e/c9b090aa-8c65-46c8-bf05-0bdc11735a5e/Conceivable-2.png Research Papers - Automated Oocyte Retrieval, Denudation, Sperm Preparation, and ICSI in the IVF Laboratory: a Proof-of-Concept Study and Report of the First Live Births - Make it stand out Whatever it is, the way you tell your story online can make all the difference. https://images.squarespace-cdn.com/content/v1/67b94584cb4968452d57305e/be98a3a5-6032-4ac8-b9fd-8f4b5347f5ad/Conceivable-3.jpeg Research Papers - Automated Oocyte Retrieval, Denudation, Sperm Preparation, and ICSI in the IVF Laboratory: a Proof-of-Concept Study and Report of the First Live Births - Figure 2. Illustration of the horizontal swim-out process. (A) The HSO configuration. Following liquefaction, 2 μl aliquots of the raw ejaculate were added to #1 droplet, containing 5 μl of MHM-C. Each of these semen-containing droplets was connected via a 1 cm long horizontal channel to an intermediate droplet (#2) containing 10 μl of MHM-C. These intermediate droplets were then connected through 0.5 cm long channel at a 90-degree angle to a 5 μl 7% PVP droplet (#3). Motile sperm migrates through the connected droplets, from the raw ejaculate droplets to the last (third) drop, following the direction pointed by the arrows. (B) Illustration of channel cut position, which occurs after a predefined sperm concentration is reached. (C) Four HSO configurations in the same dish were used for each sperm preparation procedure. Figure 2. Illustration of the horizontal swim-out process. (A) The HSO configuration. Following liquefaction, 2 μl aliquots of the raw ejaculate were added to #1 droplet, containing 5 μl of MHM-C. Each of these semen-containing droplets was connected via a 1 cm long horizontal channel to an intermediate droplet (#2) containing 10 μl of MHM-C. These intermediate droplets were then connected through 0.5 cm long channel at a 90-degree angle to a 5 μl 7% PVP droplet (#3). Motile sperm migrates through the connected droplets, from the raw ejaculate droplets to the last (third) drop, following the direction pointed by the arrows. (B) Illustration of channel cut position, which occurs after a predefined sperm concentration is reached. (C) Four HSO configurations in the same dish were used for each sperm preparation procedure. https://images.squarespace-cdn.com/content/v1/67b94584cb4968452d57305e/98661447-933b-4d3b-899c-06ebc1a27150/Conceivable-4.jpeg Research Papers - Automated Oocyte Retrieval, Denudation, Sperm Preparation, and ICSI in the IVF Laboratory: a Proof-of-Concept Study and Report of the First Live Births - Figure 3. Overview of an automated system for oocyte handling and denudation (Pearl 2). (A) Enclosed system overview showing two Cartesian robots (top and bottom) separated by an intermediate heated stage for housing dishes. (B) Detailed view of the custom 3D-printed dish holder adapter, resting on the heated stage. In this configuration, the top Cartesian robot is equipped with a 4× objective and dual Narishige microtool holders to support oocyte denudation. https://images.squarespace-cdn.com/content/v1/67b94584cb4968452d57305e/dbc7a6ee-8863-489d-9ce6-1c31ee5fe2b2/Conceivable-5.png Research Papers - Automated Oocyte Retrieval, Denudation, Sperm Preparation, and ICSI in the IVF Laboratory: a Proof-of-Concept Study and Report of the First Live Births - Make it stand out Sperm Provider 3 produced a small ejaculate, which could not feasibly be split in two parts and was instead used for manual sperm preparation only. HSO, horizontal swim out; DGC, density gradient centrifugation; HPF, high power field of vision; N/A, data not available. https://images.squarespace-cdn.com/content/v1/67b94584cb4968452d57305e/14f400cb-ddc4-49dd-80d2-cca3be9967cc/Conceivable-6.png Research Papers - Automated Oocyte Retrieval, Denudation, Sperm Preparation, and ICSI in the IVF Laboratory: a Proof-of-Concept Study and Report of the First Live Births - Make it stand out Autolog, autologous; DOR, diminished ovarian reserve; E2, oestradiol; N/A, data not available; PCOS, polycystic ovary syndrome; POI, primary ovarian insufficiency; Unexpl, unexplained, idiopathic; Recipr, reciprocal. https://images.squarespace-cdn.com/content/v1/67b94584cb4968452d57305e/714864b7-212a-4aea-a5aa-2fc660c7044d/Conceivable-Table-4.png Research Papers - Automated Oocyte Retrieval, Denudation, Sperm Preparation, and ICSI in the IVF Laboratory: a Proof-of-Concept Study and Report of the First Live Births - Make it stand out Pt, patient; P1, Pearl 1, sperm preparation; SU, swim-up; HSO, horizontal swim-out; P2, cumulus–oocyte complex (COC) retrieval and oocyte denudation; R1, Routine 1, follicular fluid search; R2, Routine 2, COC isolation; R3, Routine 3, oocyte denudation; P3, Pearl 3, ICSI; N/A, not applicable. Fertilization rate was defined as number of 2PN zygotes at 16–18 h post-insemination divided by the number of injected oocytes. The total number of eggs reported for each patient does not necessarily match the total number of mature eggs reported in Table 3. This is because, on occasion, eggs were vitrified for future use, or were allocated to a single Pearl only, and were thus excluded from this report. a Two COCs from this patient were lost during manipulation with the Pearl 2 system. b During two separate transfers. https://images.squarespace-cdn.com/content/v1/67b94584cb4968452d57305e/7889bc57-b10b-4de2-9e37-c2d44165fb48/Conceivable-5.jpeg Research Papers - Automated Oocyte Retrieval, Denudation, Sperm Preparation, and ICSI in the IVF Laboratory: a Proof-of-Concept Study and Report of the First Live Births - Figure 4. Embryo morphology and transfer results. Embryo morphology was classified according to Gardner and Schoolcraft (1999) and by using the artificial intelligence assistant ERICA (Chavez-Badiola et al., 2020), which provides both a qualitative and quantitative score ranging between 0 and 1. Both Garnder and ERICA scores were assigned pre-vitrification. Negative pregnancy was defined as a blood beta hCG measurement lower than 20 IU/ml; biochemical pregnancy loss as decreasing serum or urinary beta hCG levels before ultrasound evaluation; early pregnancy loss as spontaneous loss before 10 weeks gestation. Scale bars equal ∼50 µm. Figure 4. Embryo morphology and transfer results. Embryo morphology was classified according to Gardner and Schoolcraft (1999) and by using the artificial intelligence assistant ERICA (Chavez-Badiola et al., 2020), which provides both a qualitative and quantitative score ranging between 0 and 1. Both Garnder and ERICA scores were assigned pre-vitrification. Negative pregnancy was defined as a blood beta hCG measurement lower than 20 IU/ml; biochemical pregnancy loss as decreasing serum or urinary beta hCG levels before ultrasound evaluation; early pregnancy loss as spontaneous loss before 10 weeks gestation. Scale bars equal ∼50 µm. https://images.squarespace-cdn.com/content/v1/67b94584cb4968452d57305e/dcee1288-928d-423a-bc0f-ad099e609a0d/Table-5.png Research Papers - Automated Oocyte Retrieval, Denudation, Sperm Preparation, and ICSI in the IVF Laboratory: a Proof-of-Concept Study and Report of the First Live Births - Make it stand out Pt, patient; P1, sperm preparation; P2, cumulus–oocyte complex (COC) retrieval and oocyte denudation; P3, ICSI; SU, swim-up; HSO, horizontal swim out. Negative pregnancy test was defined as beta hCG lower than 20 IU/ml. Biochemical pregnancy loss was defined as decreasing serum or urinary beta hCG levels, before an ultrasound evaluation. Early pregnancy loss was defined as spontaneous pregnancy loss before 10 weeks gestation. Definitions are based on (Kolte et al., 2015). https://www.conceivable.life/research-papers/a-methodology-for-activity-basedcosting-to-scale-ivf-lab-operations monthly 0.5 2026-02-26 https://images.squarespace-cdn.com/content/v1/67b94584cb4968452d57305e/a2a38091-3696-4427-b086-336e6ebb251d/Screenshot+2026-02-25+at+6.23.28%E2%80%AFPM.png Research Papers - A Methodology for Activity-Based Costing to Scale IVF Lab Operations - Make it stand out Whatever it is, the way you tell your story online can make all the difference. https://images.squarespace-cdn.com/content/v1/67b94584cb4968452d57305e/80ccb071-f76e-4a9b-9b11-5af292e86606/Screenshot+2026-02-25+at+6.25.20%E2%80%AFPM.png Research Papers - A Methodology for Activity-Based Costing to Scale IVF Lab Operations - Make it stand out Whatever it is, the way you tell your story online can make all the difference. https://images.squarespace-cdn.com/content/v1/67b94584cb4968452d57305e/3f93f2f8-7d80-4f93-af81-8069e349db86/Screenshot+2026-02-25+at+6.30.36%E2%80%AFPM.png Research Papers - 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A Methodology for Activity-Based Costing to Scale IVF Lab Operations - Make it stand out Whatever it is, the way you tell your story online can make all the difference. https://images.squarespace-cdn.com/content/v1/67b94584cb4968452d57305e/fafbde75-4553-4725-81c4-a88558df54bc/Screenshot+2026-02-25+at+6.38.18%E2%80%AFPM.png Research Papers - A Methodology for Activity-Based Costing to Scale IVF Lab Operations - Make it stand out Whatever it is, the way you tell your story online can make all the difference. https://images.squarespace-cdn.com/content/v1/67b94584cb4968452d57305e/983e4d42-1bb4-4093-a70e-db15876d10c4/Screenshot+2026-02-25+at+6.39.27%E2%80%AFPM.png Research Papers - A Methodology for Activity-Based Costing to Scale IVF Lab Operations - Make it stand out Whatever it is, the way you tell your story online can make all the difference. https://images.squarespace-cdn.com/content/v1/67b94584cb4968452d57305e/2b0d5dc3-b7c4-4f27-9f07-404609cb8610/Screenshot+2026-02-25+at+6.41.31%E2%80%AFPM.png Research Papers - A Methodology for Activity-Based Costing to Scale IVF Lab Operations - Make it stand out Note: The percentages for semen freezing, IUI and FET represent the ratio of these procedures to the base 2000 egg/IVF cycles. https://images.squarespace-cdn.com/content/v1/67b94584cb4968452d57305e/7ae6d729-78c0-4ea5-8cd6-dd94c5a89170/Screenshot+2026-02-25+at+6.43.39%E2%80%AFPM.png Research Papers - A Methodology for Activity-Based Costing to Scale IVF Lab Operations - Make it stand out Total annual standard hours: 19,251 embryologist hours and 11,825 andrologist hours This translates to staffing requirements of approximately 12.9 embryologists and 7.9 andrologists. https://images.squarespace-cdn.com/content/v1/67b94584cb4968452d57305e/c026e32a-b3ac-4b60-869e-c178dfe2ad07/Screenshot+2026-02-25+at+6.45.05%E2%80%AFPM.png Research Papers - A Methodology for Activity-Based Costing to Scale IVF Lab Operations - Make it stand out Whatever it is, the way you tell your story online can make all the difference. https://images.squarespace-cdn.com/content/v1/67b94584cb4968452d57305e/f4e25ef3-2362-4a9c-99f6-9e5662124617/Screenshot+2026-02-25+at+6.46.20%E2%80%AFPM.png Research Papers - A Methodology for Activity-Based Costing to Scale IVF Lab Operations - Make it stand out Whatever it is, the way you tell your story online can make all the difference. https://images.squarespace-cdn.com/content/v1/67b94584cb4968452d57305e/9cf89404-2c6b-47ec-9eb5-01dbb7c6f445/Screenshot+2026-02-25+at+6.50.05%E2%80%AFPM.png Research Papers - A Methodology for Activity-Based Costing to Scale IVF Lab Operations - Make it stand out *Note: Some labs only use IVF LAF workbenches instead of CO2 Isolettes based on Air Handling Unit (AHU) and media https://images.squarespace-cdn.com/content/v1/67b94584cb4968452d57305e/68b2d0e0-6f67-490f-aec2-38d4a024b7c8/Screenshot+2026-02-25+at+6.51.36%E2%80%AFPM.png Research Papers - A Methodology for Activity-Based Costing to Scale IVF Lab Operations - Make it stand out *Annual capital charge includes maintenance, calibration, and WACC charge of 12% for equipment AND space build cost ^ Blend of IVF LAF workbenches with and without scopes and heated plates ~ Blended average of benchtop and time-lapse incubators https://images.squarespace-cdn.com/content/v1/67b94584cb4968452d57305e/c5b06efe-6400-4bc1-a6ff-09e951217309/Screenshot+2026-02-25+at+6.52.29%E2%80%AFPM.png Research Papers - A Methodology for Activity-Based Costing to Scale IVF Lab Operations - Make it stand out Whatever it is, the way you tell your story online can make all the difference. https://images.squarespace-cdn.com/content/v1/67b94584cb4968452d57305e/7c391690-72ce-4ddb-b7e5-541a988810f8/Screenshot+2026-02-25+at+6.54.00%E2%80%AFPM.png Research Papers - A Methodology for Activity-Based Costing to Scale IVF Lab Operations - Make it stand out Whatever it is, the way you tell your story online can make all the difference. https://images.squarespace-cdn.com/content/v1/67b94584cb4968452d57305e/40e1c754-696a-4f3c-869f-fb6b2f18a757/Screenshot+2026-02-25+at+6.55.58%E2%80%AFPM.png Research Papers - A Methodology for Activity-Based Costing to Scale IVF Lab Operations - Make it stand out Figure 3: Activity-based costing for a 2000-cycle lab (Procedures and Equipment Usage) https://images.squarespace-cdn.com/content/v1/67b94584cb4968452d57305e/f9730fb8-0872-4fbc-9c41-9524b9e368d1/Screenshot+2026-02-25+at+6.58.24%E2%80%AFPM.png Research Papers - A Methodology for Activity-Based Costing to Scale IVF Lab Operations - Make it stand out Whatever it is, the way you tell your story online can make all the difference. https://images.squarespace-cdn.com/content/v1/67b94584cb4968452d57305e/d63c83a6-306f-491c-8946-6166d621e8fc/Screenshot+2026-02-25+at+6.59.21%E2%80%AFPM.png Research Papers - A Methodology for Activity-Based Costing to Scale IVF Lab Operations - Make it stand out Whatever it is, the way you tell your story online can make all the difference. https://images.squarespace-cdn.com/content/v1/67b94584cb4968452d57305e/e5938928-3cea-462e-8e9f-79d1b1436692/Screenshot+2026-02-25+at+7.01.11%E2%80%AFPM.png Research Papers - A Methodology for Activity-Based Costing to Scale IVF Lab Operations - Make it stand out Whatever it is, the way you tell your story online can make all the difference. https://images.squarespace-cdn.com/content/v1/67b94584cb4968452d57305e/62388233-2fc5-4f71-8a50-3d842ea1a8ff/Screenshot+2026-02-25+at+7.06.09%E2%80%AFPM.png Research Papers - A Methodology for Activity-Based Costing to Scale IVF Lab Operations - Make it stand out Whatever it is, the way you tell your story online can make all the difference. https://www.conceivable.life/research-papers/the-future-use-of-ai-to-improve-accessibility-of-assisted-reproductive-technology-art-in-low-and-middle-income-countries monthly 0.5 2026-02-23 https://www.conceivable.life/research-papers/artificial-intelligence-in-assisted-reproductive-technology-separating-the-dream-from-reality monthly 0.5 2026-01-29 https://www.conceivable.life/research-papers/the-potential-of-the-automated-ivf-lab monthly 0.5 2026-02-25 https://www.conceivable.life/research-papers/shaping-the-future-of-the-ivf-laboratory-standardization-for-more-predictable-outcomes monthly 0.5 2026-02-25 https://www.conceivable.life/research-papers/activity-based-costing-in-ivf-a-framework-for-transparency-and-operational-scaling-of-fertility-services monthly 0.5 2026-02-24 https://images.squarespace-cdn.com/content/v1/67b94584cb4968452d57305e/3e7b3ea8-84d6-4a5e-9120-58dd6aabdf0e/Table-01.png Research Papers - Activity-Based Costing in IVF: A Framework for Transparency and Operational Scaling of Fertility Services - Make it stand out Table 1 Characteristics of the US-based IVF centers evaluated in the analysis. Annual Egg Retrieval Cycles are defined as completed oocyte retrievals per year. Total Annual ART Cycles include all ART procedures per year (egg retrievals plus frozen embryo transfers). The laboratory space calculation encompasses embryology, andrology, cryostorage, lab offices, preparation areas, and all spaces required to support the specified number of lab personnel and work volumes. The capacities shown represent actual operational levels during the study period, not maximum theoretical capacity https://images.squarespace-cdn.com/content/v1/67b94584cb4968452d57305e/d8ea8ac2-7998-4fee-b523-93ef7f6d4af6/Table-02.png Research Papers - Activity-Based Costing in IVF: A Framework for Transparency and Operational Scaling of Fertility Services - Make it stand out Table 2 Result summary of timed studies at the five participating centers reporting on multiple key laboratory processes. Each reported procedure timing features both a fixed and a variable time component which are combined together to calculate the procedure’s total time. Calculation used the 95th centile for the distribution of each time measurement series to ensure a robust and conservative time estimate. Importantly, timings capture the complete labor cost component of each procedure, including direct procedural time, ancillary administrative tasks, witnessing, setup, cleanup, and necessary idle time. For comparison, timings presented in recent literature for the same procedures are also reported https://images.squarespace-cdn.com/content/v1/67b94584cb4968452d57305e/d48a20bd-a5d6-43f7-90f0-48ab04f3897f/Table-03.png Research Papers - Activity-Based Costing in IVF: A Framework for Transparency and Operational Scaling of Fertility Services - Make it stand out Table 3 Calculated timings for complete laboratory workflows (stringing multiple procedures) offering a breakdown between embryologist and andrologist time contributions. Times represent total laboratory commitment including preparation, procedure execution, monitoring, quality checks, and documentation across the full workflow, not solely hands-on manipulation time. “Complete workflows” include all laboratory activities from sperm/egg processing through cryopreservation, encompassing preparation, insemination, culture monitoring, quality control, and documentation. The table further offers a comparison of our findings against recent published literature https://images.squarespace-cdn.com/content/v1/67b94584cb4968452d57305e/9005a413-9f93-457c-b25c-ccce1d6ed0f5/CoastingIVF.jpg Research Papers - Activity-Based Costing in IVF: A Framework for Transparency and Operational Scaling of Fertility Services - Make it stand out Figure 1 Queuing Rule of Thumb (QROT) analysis of staff productivity gain. Centers performing a higher number of egg collections per day use proportionally less staff time per procedure https://images.squarespace-cdn.com/content/v1/67b94584cb4968452d57305e/351bea23-2983-47dd-8280-8a2e52dd02eb/CoastingIVF-02.jpg Research Papers - Activity-Based Costing in IVF: A Framework for Transparency and Operational Scaling of Fertility Services - Make it stand out Figure 2 Average costs by procedure type at a center performing 2000 yearly egg retrieval cycles https://images.squarespace-cdn.com/content/v1/67b94584cb4968452d57305e/6d84d0ca-6f3b-4cee-917a-89455674f2d0/ScaleEconomics.png Research Papers - Activity-Based Costing in IVF: A Framework for Transparency and Operational Scaling of Fertility Services - Make it stand out Figure 3 Cost variation by egg count for different procedures at a center offering 2000 egg retrieval cycles/year. A typical center charges a fixed fee while costs vary with the number of eggs retrieved. For each procedure, we present the average fees charged across participating centers and calculate what percentage of this fee is used to cover for true lab costs based on biological input https://images.squarespace-cdn.com/content/v1/67b94584cb4968452d57305e/6ca53bbb-4147-4363-9b5f-dc5f38d2130c/ScaleEconomics2.png Research Papers - Activity-Based Costing in IVF: A Framework for Transparency and Operational Scaling of Fertility Services - Make it stand out Figure 4 A comparative overview for the total economic cost of ICSI and embryo biopsy plus embryo cryostorage between IVF centers of different sizes (500 to 4000 egg retrieval cycles per year), based on number of eggs treated. Larger centers typically achieve greater cost-efficiency https://images.squarespace-cdn.com/content/v1/67b94584cb4968452d57305e/2ba4d724-f9e4-4cb3-ba73-353e12b26fbf/SupInfo.png Research Papers - Activity-Based Costing in IVF: A Framework for Transparency and Operational Scaling of Fertility Services - Make it stand out Whatever it is, the way you tell your story online can make all the difference. https://www.conceivable.life/research-papers/use-and-understanding-of-ai-in-the-art-laboratory-an-international-survey monthly 0.5 2026-02-25 https://www.conceivable.life/research-papers/a-digitally-controlled-remotely-operated-icsi-system-case-report-of-the-first-live-birth monthly 0.5 2026-02-17 https://images.squarespace-cdn.com/content/v1/67b94584cb4968452d57305e/15cd376b-1e90-467c-845f-10355e22ca98/gr1_lrg.jpg Research Papers - A Digitally Controlled, Remotely Operated ICSI System: Case Report of the First Live Birth - Make it stand out Figure 1 The remote intracytoplasmic sperm injection experimental set-up, adapted from a standard micromanipulation workstation, modified to incorporate fully motorized and digitally controlled components for remote operation. https://images.squarespace-cdn.com/content/v1/67b94584cb4968452d57305e/a73c56e8-f635-42f4-a32f-66467d2e1db2/Screenshot+2026-01-23+at+10.48.46%E2%80%AFAM.png Research Papers - A Digitally Controlled, Remotely Operated ICSI System: Case Report of the First Live Birth - Make it stand out Whatever it is, the way you tell your story online can make all the difference. https://images.squarespace-cdn.com/content/v1/67b94584cb4968452d57305e/a00ff6c6-df2d-4062-8fa8-04bd95fe6539/gr2_lrg.jpg Research Papers - A Digitally Controlled, Remotely Operated ICSI System: Case Report of the First Live Birth - Make it stand out Figure 2 Fresh transfer of a good-quality blastocyst produced by remote intracytoplasmic sperm injection (ICSI) (A) did not result in pregnancy. A cryopreserved blastocyst produced by remote ICSI re-expanded within 4 h after warming (B) resulted in a clinical pregnancy after assisted hatching and embryo transfer (C). https://www.conceivable.life/research-papers/preclinical-validation-of-fast-oocyte-vitrification-and-warming-protocols-with-comparable-efficiencies-to-a-standard-method monthly 0.5 2026-02-25 https://www.conceivable.life/research-papers/investigating-phototoxicity-of-optical-coherence-tomography-oct-imaging-in-porcine-and-human-sperm monthly 0.5 2026-02-25 https://images.squarespace-cdn.com/content/v1/67b94584cb4968452d57305e/007c7ade-ef7f-453d-b93e-828a7d43f78a/IPO-01.jpg Research Papers - Investigating Phototoxicity of Optical Coherence Tomography (OCT) Imaging in Porcine and Human Sperm - Make it stand out Figure 1 Schematic diagram of the optical set-up for optical coherence tomography (OCT) imaging and irradiation experiments. The set-up comprises two modes: irradiation mode (represented on blue background) and OCT mode (represented on yellow background). The OCT interferometer consists of a fibre coupler that splits light from the tuneable laser source into the sample arm and reference arm. The light in the sample arm interacts with the specimen, and is collected back through the same path. https://images.squarespace-cdn.com/content/v1/67b94584cb4968452d57305e/6979af95-2952-429d-9d7f-6a436d02e52e/IPO-02.jpg Research Papers - Investigating Phototoxicity of Optical Coherence Tomography (OCT) Imaging in Porcine and Human Sperm - Make it stand out Figure 2 (a) Diagram of Petri dish and arrangement of culture media droplets. The irradiated area is shown. (b) Description of the scanning protocols (A–D) showing the operation of the point-scanning optical coherence tomography system. Md, media droplet. https://images.squarespace-cdn.com/content/v1/67b94584cb4968452d57305e/0d4dc2ea-36e5-4955-b5ed-1cc13727d386/IPO-03.jpg Research Papers - Investigating Phototoxicity of Optical Coherence Tomography (OCT) Imaging in Porcine and Human Sperm - Make it stand out Figure 3 (a) Diagram of scanning pattern over sample in a well of a multi-well dish during the optical coherence tomography time lapse of porcine cumulus–oocyte complexes (COC) with irradiated spermatozoa. (b) Image processing routine for data analysis. For the three-dimensional dataset of each COC, co-localization analysis was performed at two depth slices: one intersecting the oocyte and part of the cumulus cells around the oocyte (‘through’ slice), and one above the oocyte, intersecting the cumulus cells alone (‘away’ slice). https://images.squarespace-cdn.com/content/v1/67b94584cb4968452d57305e/be60fc0b-78b9-4e8c-95e2-e520c5c33893/IPO-04.png Research Papers - Investigating Phototoxicity of Optical Coherence Tomography (OCT) Imaging in Porcine and Human Sperm - Make it stand out TABLE 1 Parameters of boar spermatozoa following irradiation with varying overall irradiation time at constant scanning frequency Values represent mean ± SE. This experiment was repeated three times using three different boar ejaculates. Degrees of freedom = 3, given four sample groups with different exposure conditions. Control samples were non-irradiated samples. Values were compared by Kruskal–Wallis test. https://images.squarespace-cdn.com/content/v1/67b94584cb4968452d57305e/70176332-7fae-4c85-bcfd-b5f0c0dff00a/IPO-05.jpg Research Papers - Investigating Phototoxicity of Optical Coherence Tomography (OCT) Imaging in Porcine and Human Sperm - Make it stand out Figure 4 Boar and human sperm motility parameters when subjected to various conditions (Protocols A–D): (A) boar spermatozoa subjected to varied overall irradiation time; (B) boar spermatozoa subjected to varied scanning frequency; (C) boar spermatozoa subjected to varying optical coherence tomography angiography line scan repetition; (D) human spermatozoa irradiated with two different optical powers. Control samples are non-irradiated samples. No significant differences were found between groups for average path velocity (VAP), straight line velocity (VSL) and curvilinear line velocity (VCL) for each protocol according to the Kruskal–Wallis test (see Supplementary Table for P-values). N, number of scan repetitions. Error bars represent standard error. https://images.squarespace-cdn.com/content/v1/67b94584cb4968452d57305e/9140d231-35d8-4942-b4a1-9d510489b511/IP_tbl2.png Research Papers - Investigating Phototoxicity of Optical Coherence Tomography (OCT) Imaging in Porcine and Human Sperm - Make it stand out TABLE 2 Parameters of boar spermatozoa following irradiation with varying scanning frequency and constant overall irradiation time Values represent mean ± SE. This experiment was repeated five times using five different boar ejaculates. Degrees of freedom = 3, given four sample groups with different exposure conditions. Control samples were non-irradiated samples. Values were compared by Kruskal–Wallis test. https://images.squarespace-cdn.com/content/v1/67b94584cb4968452d57305e/544d4f0b-eeb7-4a73-8346-bc6fe8d41ae7/IP-tbl3.png Research Papers - Investigating Phototoxicity of Optical Coherence Tomography (OCT) Imaging in Porcine and Human Sperm - Make it stand out TABLE 3 Parameters of boar spermatozoa following irradiation with varying optical coherence tomography angiography (OCT-A) line scan repetitions Values represent mean ± SE. This experiment was repeated three times using three different boar ejaculates. Degrees of freedom = 3, given four sample groups with different exposure conditions. Control samples were non-irradiated samples. Values were compared by Kruskal–Wallis test. https://images.squarespace-cdn.com/content/v1/67b94584cb4968452d57305e/f5f03920-d264-4cf9-b53e-b93d4008259c/ip-img3.jpg Research Papers - Investigating Phototoxicity of Optical Coherence Tomography (OCT) Imaging in Porcine and Human Sperm - Make it stand out Figure 5 Analysis of sample dynamics across the time-lapse duration. (a) Co-localization analysis, evolution of M2 coefficient between a given frame and the reference frame at t0. The evolution of M2 against time is shown in shades of blue for the control cumulus–oocyte complex (COC) (control dish), and in shades of yellow for the irradiated COC (irradiation dish). For each sample, data from two depths are considered. Frames were acquired at 5-min intervals. (b–e) Logarithm intensity variance (LIV) maps obtained with the same frames. In LIV maps, red corresponds to low dynamics and green corresponds to high dynamics. Map brightness corresponds to the logarithmic optical coherence tomography intensity. https://images.squarespace-cdn.com/content/v1/67b94584cb4968452d57305e/fc7b6569-5cc8-4514-949f-49a3aeae0b60/IP-tbl4.png Research Papers - Investigating Phototoxicity of Optical Coherence Tomography (OCT) Imaging in Porcine and Human Sperm - Make it stand out TABLE 4 Parameters of human spermatozoa following varying irradiation power values Values represent mean ± SE. This experiment was repeated using six different human ejaculates from three donors. Degrees of freedom = 2, given three sample groups with different exposure conditions. Control samples were non-irradiated samples. Values were compared by Kruskal–Wallis test. https://images.squarespace-cdn.com/content/v1/67b94584cb4968452d57305e/0d33d5d8-1d66-424b-b04b-956b2417bc88/InvestigatingPhototoxicity_doc.png Research Papers - Investigating Phototoxicity of Optical Coherence Tomography (OCT) Imaging in Porcine and Human Sperm - Make it stand out Whatever it is, the way you tell your story online can make all the difference. https://www.conceivable.life/research-papers/advancing-icsi-robotics-follow-up-on-the-transition-from-remote-to-fully-automated-intracytoplasmic-sperm-injection monthly 0.5 2026-02-24 https://www.conceivable.life/research-papers/pre-clinical-validation-of-an-ai-powered-automated-robotic-intracytoplasmic-sperm-injection-system monthly 0.5 2026-02-23 https://www.conceivable.life/research-papers/real-time-automated-detection-of-human-cumulus-oocyte-complexes-using-high-resolution-imaging-and-ai-inference-2 monthly 0.5 2026-02-25 https://www.conceivable.life/research-papers/real-time-automated-detection-of-human-cumulus-oocyte-complexes-using-high-resolution-imaging-and-ai-inference-29scd monthly 0.5 2026-01-12 https://www.conceivable.life/research-papers/high-viscosity-mineral-oils-provide-enhanced-protection-to-embryo-culture-systems-against-volatile-organic-compounds-induced-embryotoxicity monthly 0.5 2026-02-23 https://www.conceivable.life/research-papers/can-ai-guided-feedback-improve-embryologists-selection-of-euploid-embryos-based-on-morphology-alone monthly 0.5 2026-02-25 https://images.squarespace-cdn.com/content/v1/67b94584cb4968452d57305e/bc7fc300-e53e-4794-8233-0dab0b5f2213/AI-guided-01.jpg Research Papers - Can AI-Guided Feedback Improve Embryologists' Selection of Euploid Embryos Based on Morphology Alone? - Make it stand out Figure 1 Synthetic cycle creation process by which the ‘cases’ presented in the selection tool were created. DB = database. https://images.squarespace-cdn.com/content/v1/67b94584cb4968452d57305e/a3b1aab1-82bf-4309-9401-3cce035a6e52/AI-guided-02.jpg Research Papers - Can AI-Guided Feedback Improve Embryologists' Selection of Euploid Embryos Based on Morphology Alone? - Make it stand out Figure 2 Examples of the selection tool. In the first selection step of each exercise (A), users are asked to assess the embryo images presented and to ‘drag and drop’ the ‘best’ embryo onto the selection box. In the final selection step (B), users are asked to select an embryo to transfer. https://images.squarespace-cdn.com/content/v1/67b94584cb4968452d57305e/38a2d487-6482-4964-b433-5c68409e86e8/AI-guided-03.jpg Research Papers - Can AI-Guided Feedback Improve Embryologists' Selection of Euploid Embryos Based on Morphology Alone? - Make it stand out Figure 3 Embryologists and ERICA perform better than random. Box and whisker plots showing (A) the proportion of euploid embryos selected at the first try for embryologists based on morphology alone, ERICA and the randomizer, with post-hoc testing by Bonferroni corrected Dunn test indicating that ERICA outperforms both the embryologists and the randomizer (P = 0.002 and P = 1.629793e-15, respectively), and that the embryologists outperform the randomizer (P = 9.400497e-04); (B) the number of attempts to select a euploid embryo for embryologists, ERICA and the randomizer, with post-hoc testing by Bonferroni corrected Dunn test indicating that both the embryologists and ERICA outperform the randomizer (P = 2.952989e-04 and P = 4.413281e-09, respectively), whereas no difference was found between the embryologists and ERICA (P = 0.44). Box and whisker plots show median (interquartile range), maximum and minimum and outliers. ERICA and the randomizer performed 150 cycles each. The six junior embryologists all carried out 150 simulated cycles; the six intermediate embryologists carried out 47, 58, 140, 150, 150 and 150 simulated cycles, respectively; the seven experienced embryologists carried out 20, 20, 149, 150, 150, 150 and 150 simulated cycles, respectively. https://images.squarespace-cdn.com/content/v1/67b94584cb4968452d57305e/ca72a9ed-7113-4af2-b2eb-a3a5f9acda8d/AI-guided-04.jpg Research Papers - Can AI-Guided Feedback Improve Embryologists' Selection of Euploid Embryos Based on Morphology Alone? - Make it stand out Figure 4 Box and whisker plots showing (A) proportion of euploid embryos selected at the first try and (B) the number of attempts to select a euploid embryo (Kruskal–Wallis chi-squared = 0.16748, df = 2, P = 0.92 and Kruskal–Wallis chi-squared = 1.4176, df = 2, P = 0.49, respectively), based on morphology alone. Box and whisker plots show median (interquartile range), maximum and minimum and outliers. The six junior embryologists all carried out 150 simulated cycles; the six intermediate embryologists carried out 47, 58, 140, 150, 150 and 150 simulated cycles respectively; the seven experienced embryologists carried out 20, 20, 149, 150, 150, 150 and 150 simulated cycles, respectively. Although senior embryologists showed a trend towards better performance than those less experienced (junior and intermediate), these differences were not statistically significant. https://images.squarespace-cdn.com/content/v1/67b94584cb4968452d57305e/e2c2a240-560a-4709-a3c6-35cffa8a1f81/AI-guided-05.jpg Research Papers - Can AI-Guided Feedback Improve Embryologists' Selection of Euploid Embryos Based on Morphology Alone? - Make it stand out Figure 5 Box and whisker plots showing decisions when presented with the assessment of the embryos from ERICA; a large proportion of all career stages of embryologists changed their decisions. (A) Kruskal–Wallis chi-squared = 0.56986, df = 2, P = 0.7521). The six junior embryologists all carried out 150 simulated cycles; the six intermediate embryologists carried out 47, 58, 140, 150, 150 and 150 simulated cycles, respectively; the seven experienced embryologists carried out 20, 20, 149, 150, 150, 150 and 150 simulated cycles, respectively. No difference was found between groups of embryologists in picking a better or worse embryo; (B) Kruskal–Wallis chi-squared = 1.0682, df = 2, P = 0.5862 for the rate of decision change for the better; and (C) Kruskal–Wallis chi-squared = 0.80044, df = 2, P = 0.6702 for the rate of decision change for the worse). Box and whisker plots show median (interquartile range), maximum and minimum and outliers. https://images.squarespace-cdn.com/content/v1/67b94584cb4968452d57305e/58034aa5-6d2e-4574-bb9e-86bd46ec56a7/Image01.jpg Research Papers - Can AI-Guided Feedback Improve Embryologists' Selection of Euploid Embryos Based on Morphology Alone? - Make it stand out Image A https://images.squarespace-cdn.com/content/v1/67b94584cb4968452d57305e/f7ccaebe-c812-4117-b374-bde77d6033b7/Image02.jpg Research Papers - Can AI-Guided Feedback Improve Embryologists' Selection of Euploid Embryos Based on Morphology Alone? - Make it stand out Image B https://images.squarespace-cdn.com/content/v1/67b94584cb4968452d57305e/529bedb5-b2eb-4b9d-bc24-b4df148dfcb5/Image03.jpg Research Papers - Can AI-Guided Feedback Improve Embryologists' Selection of Euploid Embryos Based on Morphology Alone? - Make it stand out Image C https://images.squarespace-cdn.com/content/v1/67b94584cb4968452d57305e/310f96da-387c-4bfb-9cbb-37e35e15ba6b/Image04.jpg Research Papers - Can AI-Guided Feedback Improve Embryologists' Selection of Euploid Embryos Based on Morphology Alone? - Make it stand out Image D https://images.squarespace-cdn.com/content/v1/67b94584cb4968452d57305e/f6d80654-7497-4ecc-8575-69fed9286e55/Image05.jpg Research Papers - Can AI-Guided Feedback Improve Embryologists' Selection of Euploid Embryos Based on Morphology Alone? - Make it stand out Image E https://images.squarespace-cdn.com/content/v1/67b94584cb4968452d57305e/f6eb6093-46f2-4ac0-ba5e-f10c0039ebed/Image06.jpg Research Papers - Can AI-Guided Feedback Improve Embryologists' Selection of Euploid Embryos Based on Morphology Alone? - Make it stand out Image F https://images.squarespace-cdn.com/content/v1/67b94584cb4968452d57305e/fc252672-a7e3-45cb-b237-f846be2334b9/Image07.jpg Research Papers - Can AI-Guided Feedback Improve Embryologists' Selection of Euploid Embryos Based on Morphology Alone? - Make it stand out Image G https://www.conceivable.life/research-papers/validation-of-a-novel-high-capacity-automated-incubator-for-in-vitro-fertilization-ivf monthly 0.5 2026-02-25 https://www.conceivable.life/research-papers/a-novel-3d-printed-incubator-for-holding-gametes-and-embryos-during-in-vitro-fertilization-ivf-procedures monthly 0.5 2026-01-12 https://www.conceivable.life/research-papers/can-an-automated-dish-preparation-system-deliver-consistent-dish-characteristics-maintain-acceptable-media-ph-and-avoid-embryotoxic-effects monthly 0.5 2026-02-25 https://www.conceivable.life/research-papers/environmental-validation-of-a-novel-automated-ivf-platform-results-from-comprehensive-off-gassing-and-toxicity-assessment monthly 0.5 2026-02-25 https://images.squarespace-cdn.com/content/v1/67b94584cb4968452d57305e/67661259-2049-49fa-911c-30d929cf08ad/IVF-PLATFORM.png Research Papers - Environmental Validation of a Novel Automated IVF Platform: Results from Comprehensive Off-Gassing and Toxicity Assessment - Make it stand out Whatever it is, the way you tell your story online can make all the difference. https://www.conceivable.life/research-papers/pilot-clinical-evaluation-of-an-automatic-horizontal-sperm-swim-out-method-for-semen-preparation-2 monthly 0.5 2026-02-25 https://www.conceivable.life/research-papers/artificial-intelligence-in-human-reproduction monthly 0.5 2026-02-25 https://www.conceivable.life/research-papers/use-of-artificial-intelligence-embryo-selection-based-on-static-images-to-predict-first-trimester-pregnancy-loss monthly 0.5 2026-02-25 https://images.squarespace-cdn.com/content/v1/67b94584cb4968452d57305e/3f1c9c0e-3132-4d89-ae25-2dee3d6c16b1/EmbryoSelection-01.jpg Research Papers - Use of Artificial Intelligence Embryo Selection Based on Static Images to Predict First-Trimester Pregnancy Loss - Figure 1 Figure 1 Number of embryo transfer cycles performed in the study period (August 2019–May 2021) and detailed inclusion process. FHB, fetal heart beat. https://images.squarespace-cdn.com/content/v1/67b94584cb4968452d57305e/25a58258-b005-44da-bca1-10f708e456a2/EmbryoSelection-02.png Research Papers - Use of Artificial Intelligence Embryo Selection Based on Static Images to Predict First-Trimester Pregnancy Loss - Make it stand out Table 1 Demographic information Data are n (%) unless otherwise indicated. a All spontaneous abortions before 7–8 weeks, including those with no identifiable fetal heart beat. b. For clarity, ‘maternal age’ refers to recipient age in all cycles (including donor cycles). https://images.squarespace-cdn.com/content/v1/67b94584cb4968452d57305e/5b6c355e-a7fb-43aa-9370-3fae4ae28d66/EmbryoSelection-03.jpg Research Papers - Use of Artificial Intelligence Embryo Selection Based on Static Images to Predict First-Trimester Pregnancy Loss - Make it stand out Figure 2 Spontaneous abortion proportions by ERICA rank: (a) overall; and (b) stratified by recipient age group (≤35, 36–38 or ≥39 years). ERICA rank: optimal, score ≥0.70; good, score ≥0.50 and <0.70; fair: score ≥0.30 and <0.50; poor: https://images.squarespace-cdn.com/content/v1/67b94584cb4968452d57305e/74ff0ee8-538d-43f5-8618-73769141a610/EmbryoSelection-04.png Research Papers - Use of Artificial Intelligence Embryo Selection Based on Static Images to Predict First-Trimester Pregnancy Loss - Make it stand out Table 2 Incidence of spontaneous abortion by ERICA embryo rank and recipient age SA, spontaneous abortion (early pregnancy loss). https://images.squarespace-cdn.com/content/v1/67b94584cb4968452d57305e/2c7403f3-e860-4a7f-a140-83fa5ff394eb/EmbryoSelection-appx.png Research Papers - Use of Artificial Intelligence Embryo Selection Based on Static Images to Predict First-Trimester Pregnancy Loss - Make it stand out For each subset, total sample size (n) is given, together with number and calculated percentage incidence of spontaneous abortion (SA) per group. Age groups determined by recipient age (years). https://www.conceivable.life/research-papers/a-fully-automated-semen-preparation-robot monthly 0.5 2026-02-25 https://images.squarespace-cdn.com/content/v1/67b94584cb4968452d57305e/13e17ac5-b46b-4bc5-86c8-ee4ce9f5a76c/SeamanRobot.png Research Papers - A Fully Automated Semen Preparation Robot - Make it stand out Table 1. Comparison of prepared sperm parameters and ICSI outcomes between robotic-assisted and traditional semen preparation in pilot clinical trial. DSU = Direct Swim Up; DGC = Density Gradient Centrifugation. *One patient had one fresh and one vitrified/warmed blastocyst transfer. https://www.conceivable.life/research-papers/an-ai-driven-robotic-system-for-egg-retrieval-and-denudation monthly 0.5 2026-02-25 https://images.squarespace-cdn.com/content/v1/67b94584cb4968452d57305e/93ab8ac5-8541-448d-8d9e-cf407124768b/RobotEggDelivery.png Research Papers - An AI-Driven Robotic System for Egg Retrieval and Denudation - Make it stand out Whatever it is, the way you tell your story online can make all the difference. https://www.conceivable.life/research-papers/laser-immobilization-of-sperm-for-icsi monthly 0.5 2026-02-25 https://www.conceivable.life/research-papers/complex-master-slave-enhanced-optical-coherence-microscopy monthly 0.5 2026-02-25 https://images.squarespace-cdn.com/content/v1/67b94584cb4968452d57305e/40729351-708f-4ebd-8dc5-4a63f7c9c823/Equation2.png Research Papers - Complex Master-Slave Enhanced Optical Coherence Microscopy - Make it stand out Whatever it is, the way you tell your story online can make all the difference. https://images.squarespace-cdn.com/content/v1/67b94584cb4968452d57305e/62f7bc89-7834-4271-a6fb-01fae6e079f3/Equation1.png Research Papers - Complex Master-Slave Enhanced Optical Coherence Microscopy - Make it stand out Whatever it is, the way you tell your story online can make all the difference. https://images.squarespace-cdn.com/content/v1/67b94584cb4968452d57305e/c1ef3758-200a-4940-b984-6aeb6b750b68/getimagev2.jpeg Research Papers - Complex Master-Slave Enhanced Optical Coherence Microscopy - Make it stand out Fig. 1. Diagram of the SD-OCM set-up. SC: Supercontinuum source, FB: Filtering box, MO: Microscope objective, NDF: Neutral density filter, FC: Fiber coupler, PC: Polarization controller, C: Fiber collimator, RM: Reference mirror, RTS: Reference translation stage, P: 1.5” post, XGS/YGS: X and Y galvoscanners, T: Turret, S: Sample, STS: Sample translation stage, Sp: Spectrometer, LC: Line camera, FG: Frame grabber, DAQ: Digital acquisition board, SD: Scanner driver, PSD: Power Spectral Density. https://images.squarespace-cdn.com/content/v1/67b94584cb4968452d57305e/c4160cec-86c9-4189-9831-20b10bc0e528/CharofMO1.png Research Papers - Complex Master-Slave Enhanced Optical Coherence Microscopy - Make it stand out Table 1. Characteristics of MO1, MO2, MO3 and MO4 https://images.squarespace-cdn.com/content/v1/67b94584cb4968452d57305e/1fa835c2-d6d1-4b5c-8d0e-de0033cbad4c/getimagev3.jpeg Research Papers - Complex Master-Slave Enhanced Optical Coherence Microscopy - Make it stand out Fig. 2. (a) Photograph of the four microscope objectives employed (MO1, MO2, MO3 and MO4). (b) Plot showing the axial intensity profile of the four microscope objectives employed. https://images.squarespace-cdn.com/content/v1/67b94584cb4968452d57305e/908de487-8d94-4e76-86e2-093fcb5e7184/getimagev4.jpeg Research Papers - Complex Master-Slave Enhanced Optical Coherence Microscopy - Make it stand out Fig. 3. From left to right, OCM en face slices of a USAF target obtained with MO1, MO2 and MO3. The element 3 of group 6 is circled in red. Image sizes are 650 20 µm, 285 10 µm and 171 5 µm for MO1, MO2 and MO3, respectively. https://images.squarespace-cdn.com/content/v1/67b94584cb4968452d57305e/c9c19974-89b4-4c48-a20c-a66c65f130a7/getimagev5.jpeg Research Papers - Complex Master-Slave Enhanced Optical Coherence Microscopy - Make it stand out Fig. 4. Plots of functions h (a) and (b) versus wavelength for the 3 microscope objectives studied (MO1, MO2 and M03). https://images.squarespace-cdn.com/content/v1/67b94584cb4968452d57305e/d6cf6471-daa4-4dda-8876-d306536de1d7/getimagev6.jpeg Research Papers - Complex Master-Slave Enhanced Optical Coherence Microscopy - Make it stand out Fig. 5. (a) Channeled spectrum (CS) as detected by the spectrometer line camera, obtained with system described in Fig. 1 using MO1 and a silver mirror as the sample and (b) its Fast Fourier Transform (FFT). (c) Processing of (a) using CMSI employing two sets of masks (GH1 and GH2). https://images.squarespace-cdn.com/content/v1/67b94584cb4968452d57305e/d965d72e-e4f4-477f-8e4e-5297cf7b7ebf/getimagev7.jpeg Research Papers - Complex Master-Slave Enhanced Optical Coherence Microscopy - Make it stand out Fig. 6. (a) Layout of a home-made phantom. LT: Lens Tissue. T: Double-sided tape. P: Paper. (b) to (d): B-scan images of the phantom. (b) using MO1 and mask set GH1 (c) using MO2 and mask set GH1 (d) using MO2 and mask set GH2. (e): Line intensity profiles measured at several depths, for each of the pairings in (b-d). The full width at half maximum (FWHM) of each profile is indicated in microns. https://images.squarespace-cdn.com/content/v1/67b94584cb4968452d57305e/17791d32-3feb-4d86-a4bc-805f54b8c44a/getimagev8.jpeg Research Papers - Complex Master-Slave Enhanced Optical Coherence Microscopy - Make it stand out Fig. 7. (a): Depth-averaged image of a mouse oocyte (visible in the dotted circle) immersed into PBS obtained with MO1. (b) to (d): visualizations of the same oocyte obtained with MO4. (b) B-scan image, depth along the vertical, the horizontal size is the same as that of image in (c); (c) en face image (d) depth-averaged image. The polar body (PB) is indicated by arrows in (b) to (d). https://www.conceivable.life/research-papers/multiscale-oct-imaging-for-high-throughput-assessment-of-oocytes-and-embryos monthly 0.5 2026-02-25 https://www.conceivable.life/research-papers/clustering-dynamics-of-human-spermatozoa monthly 0.5 2026-02-25 https://www.conceivable.life/research-papers/the-internet-of-things-in-assisted-reproduction monthly 0.5 2026-02-24 https://images.squarespace-cdn.com/content/v1/67b94584cb4968452d57305e/4d8d5b5e-4351-462a-bd22-fe6b44383090/gr1_lrg+%281%29.jpg Research Papers - The Internet of Things in Assisted Reproduction - Make it stand out Figure 1 Schematic representation of the data flow and implementation of an IoT system in an IVF laboratory. https://www.conceivable.life/research-papers/new-frontiers-in-embryo-selection monthly 0.5 2026-02-24 https://www.conceivable.life/research-papers/automation-in-art-paving-the-way-for-the-future-of-infertility-treatment monthly 0.5 2026-02-24 https://images.squarespace-cdn.com/content/v1/67b94584cb4968452d57305e/79321cd8-9465-4579-be2e-9da2fa66614d/IntroGraphic2.jpg Research Papers - Automation in ART: Paving the Way for the Future of Infertility Treatment - Make it stand out Graphical Abstract https://www.conceivable.life/research-papers/automated-identification-of-blastocyst-regions-at-different-development-stages monthly 0.5 2026-02-23 https://images.squarespace-cdn.com/content/v1/67b94584cb4968452d57305e/73c2bd40-9f97-4ffa-9099-976dc6c507de/Blastocycsts-01+.jpg Research Papers - Automated Identification of Blastocyst Regions at Different Development Stages - Make it stand out Figure 1 Examples of the blastocycst structures at each developmental stage, expansion (a), hatching (b), hatched (c) and collapsed (d). Colours indicate the regions of interest in the micrograph: background(BG), blastocoel (BC), zona pellucida (ZP), trophectoderm (TE), and the embryoblast or inner cell mass (ICM). https://images.squarespace-cdn.com/content/v1/67b94584cb4968452d57305e/6033256c-4998-4542-94b5-c138b076f51c/Blastocycsts-02.png Research Papers - Automated Identification of Blastocyst Regions at Different Development Stages - Make it stand out Table 1 Mean and standard deviation of Dice similarity coefficient for each region before and after the segmentation refinement step. https://images.squarespace-cdn.com/content/v1/67b94584cb4968452d57305e/d15c818f-e405-44f7-ad88-2b04ce4ec819/Blastocycsts-03.jpg Research Papers - Automated Identification of Blastocyst Regions at Different Development Stages - Make it stand out Figure 2 Examples of the original blastocyst micrographs, the images after pre-processing, before and after the segmentation refinement, and the ground truth. Please note that these images might have been stretched, shrunk, or cropped for aesthetic purposes, but the pixel values remained unaltered. https://images.squarespace-cdn.com/content/v1/67b94584cb4968452d57305e/c32c9f3f-c38e-4afe-9dbb-fae3112de6d3/Blastocycsts-04.png Research Papers - Automated Identification of Blastocyst Regions at Different Development Stages - Make it stand out Table 2 Comparison of the results by Saeedi et al., and ours in the same database. https://images.squarespace-cdn.com/content/v1/67b94584cb4968452d57305e/6c8524fb-d67d-425e-8fa5-b19192a71f38/Blastocycsts-05.jpg Research Papers - Automated Identification of Blastocyst Regions at Different Development Stages - Make it stand out Figure 3 Mean DSC for the regions of interest (x-axis) between the original blastocyst mictrographs and their transformations (y-axis) of the segmentation result. 0D, 90D, 180D, and 270D represents the rotational degrees transformation. H-, V-, and HV- represent horizontal, vertical, or both flip transformations. −100B to 100B represent the absolute value of the brightness transformation. BC Blastocoel, BG Background, ICM Inner cell mass, TE trophectoderm, ZP zona pellucida, All all the regions of interest. https://images.squarespace-cdn.com/content/v1/67b94584cb4968452d57305e/9d0e6431-a2eb-40f8-ab85-de6c816845dd/Blastocycsts-06.jpg Research Papers - Automated Identification of Blastocyst Regions at Different Development Stages - Make it stand out Figure 4 Overview of the materials and methods used in the study. https://images.squarespace-cdn.com/content/v1/67b94584cb4968452d57305e/e1f69b87-8689-44b2-ad28-e2c154b8b751/Blastocycsts-07.jpg Research Papers - Automated Identification of Blastocyst Regions at Different Development Stages - Make it stand out Figure 5 Examples of two blastocyst micrographs and the bounding pox defined by and . https://images.squarespace-cdn.com/content/v1/67b94584cb4968452d57305e/7139a4e9-e17f-4137-84e2-4468e2507fce/Blastocycsts-09.jpg Research Papers - Automated Identification of Blastocyst Regions at Different Development Stages - Make it stand out Depiction of the feature extraction process for each pixel. [F1, F2, …, F21]are filter operations, the symbol * denotes convolution, and [k1,k2, . . . ,k₍4₎1] correspond to texture extraction kernels. https://images.squarespace-cdn.com/content/v1/67b94584cb4968452d57305e/2445055e-6c1a-4782-85cc-c8e3935b15a5/Blastocycsts-08.jpg Research Papers - Automated Identification of Blastocyst Regions at Different Development Stages - Make it stand out Figure 7 Depiction of the encoder-decoder architecture employed to refine the segmentation result. https://www.conceivable.life/research-papers/time-lapse-oct-for-visualizing-eggs-and-embryos monthly 0.5 2026-02-23 https://www.conceivable.life/research-papers/artificial-intelligence-in-the-embryology-laboratory-a-review monthly 0.5 2026-02-23 https://images.squarespace-cdn.com/content/v1/67b94584cb4968452d57305e/c565cbb9-1869-4a10-be0c-e399092e9f00/GlosseryofAI-01.png Research Papers - Artificial Intelligence in the Embryology Laboratory: A Review - Make it stand out Table 1 Glossary of artificial intelligence (AI) terminology https://images.squarespace-cdn.com/content/v1/67b94584cb4968452d57305e/27a1d1bf-09e7-4fd9-aef7-1538db218d42/GlosseryofAI-02.png Research Papers - Artificial Intelligence in the Embryology Laboratory: A Review - Make it stand out Table 2 List of key advancements in the automation of IVF laboratory procedures with the aid of AI https://www.conceivable.life/research-papers/computer-software-sid-assisted-real-time-single-sperm-selection monthly 0.5 2026-02-23 https://images.squarespace-cdn.com/content/v1/67b94584cb4968452d57305e/4884e596-0e61-4069-9bf2-d5af4fb53ecd/Sperm-01.jpg Research Papers - Computer Software (SiD) Assisted Real-Time Single Sperm Selection - Make it stand out Figure 1 Processes performed by SiD. https://images.squarespace-cdn.com/content/v1/67b94584cb4968452d57305e/941202e5-1fcd-4ec1-839d-dbd9d596f507/Sperm-02.jpg Research Papers - Computer Software (SiD) Assisted Real-Time Single Sperm Selection - Make it stand out Figure 2 SiD's graphical user interface. Version SiD V1.0. The screen shows sperm selection and pick up shortly before intracytoplasmic sperm injection. https://images.squarespace-cdn.com/content/v1/67b94584cb4968452d57305e/5e5f8bfb-14da-4607-bf3c-0cd02ff07a89/Equation01.png Research Papers - Computer Software (SiD) Assisted Real-Time Single Sperm Selection - Make it stand out Whatever it is, the way you tell your story online can make all the difference. https://images.squarespace-cdn.com/content/v1/67b94584cb4968452d57305e/7a0b8259-fd0c-4de1-9b9d-e9da4b08c30b/Sperm-03.jpg Research Papers - Computer Software (SiD) Assisted Real-Time Single Sperm Selection - Make it stand out Figure 3 Sperm tracking and head movement pattern computation. Depiction of the sub-image generated around the centre of the detected sperm head and the correspondence between the sub-images of the sperm head across time and the mean intensity evolution signal S(t). https://images.squarespace-cdn.com/content/v1/67b94584cb4968452d57305e/b97e6b09-640b-447d-9f6a-e79c39758915/Equation02.png Research Papers - Computer Software (SiD) Assisted Real-Time Single Sperm Selection - Make it stand out Whatever it is, the way you tell your story online can make all the difference. https://images.squarespace-cdn.com/content/v1/67b94584cb4968452d57305e/2f5398bd-54dc-428b-9c54-53b9f33216eb/Sperm-04.jpg Research Papers - Computer Software (SiD) Assisted Real-Time Single Sperm Selection - Make it stand out Figure 4 Motility parameters by injected and non-injected spermatozoa. Box plots showing the distribution of (a) straight-line velocity (VSL); (b) linearity of the curvilinear path (LIN); and (c) head movement pattern (HMP) values of the spermatozoa in the SI set, consisting of all those spermatozoa that were selected for injection (61 spermatozoa), and the NI set, consisting of all those spermatozoa that appeared on the videos but were not injected (246 spermatozoa). *, significant differences between the means of the two sets using a Student's t-test. https://images.squarespace-cdn.com/content/v1/67b94584cb4968452d57305e/98f4ad24-b43c-4746-9250-562ed9382adc/Sperm-05.jpg Research Papers - Computer Software (SiD) Assisted Real-Time Single Sperm Selection - Make it stand out Figure 5 Motility parameters by fertilization outcome. Box plots showing the distribution of (a) straight-line velocity (VSL); (b) linearity of the curvilinear path (LIN); and (c) head movement pattern (HMP) values for the PF set, consisting of those selected and injected spermatozoa with a positive fertilization outcome (defined as the presence of two pronucei), and for the NF set, consisting of those spermatozoa with a negative fertilization result. *, significant difference between the means of the two sets using a Student's t-test. https://images.squarespace-cdn.com/content/v1/67b94584cb4968452d57305e/80d4b1df-c97f-44fb-8328-4a5bef3e6649/Sperm-06.jpg Research Papers - Computer Software (SiD) Assisted Real-Time Single Sperm Selection - Make it stand out Figure 6 Motility parameters by blastocyst formation outcome. Box plots showing the distribution of (a) straight-line velocity (VSL); (b) linearity of the curvilinear path (LIN); and (c) head movement pattern (HMP) values for the PL set, consisting of the selected and injected spermatozoa that were associated with blastocyst generation, and the NL set, consisting of the injected spermatozoa that did not result in the generation of a blastocyst. *, significant differences between the distribution of the two sets using a Mann–Whitney U-test. https://images.squarespace-cdn.com/content/v1/67b94584cb4968452d57305e/cea54604-28bc-41c8-8cdc-dd1f6717374a/Sperm-07.jpg Research Papers - Computer Software (SiD) Assisted Real-Time Single Sperm Selection - Make it stand out Figure 7 SiD score by fertilization and blastocyst formation outcomes. Box-plots showing the distribution of the SiD score values for (a) the PF set, consisting of those selected and injected spermatozoa with a positive fertilization outcome (defined as the presence of two procnuclei), and for the NF set, consisting of those spermatozoa with a negative fertilization result; and (b) the PL set, consisting of the selected and injected spermatozoa that were associated with blastocyst generation, and the NL set, consisting of the injected spermatozoa that did not result in the generation of a blastocyst. *, significant differences between the means of the two sets using a Student's t-test. https://www.conceivable.life/research-papers/automation-of-the-in-vitro-fertilization-laboratory monthly 0.5 2025-09-12 https://www.conceivable.life/research-papers/automation-of-gamete-preparation monthly 0.5 2025-09-12 https://www.conceivable.life/research-papers/erica monthly 0.5 2026-02-23 https://www.conceivable.life/research-papers/category/Full+Paper monthly 0.5 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https://images.squarespace-cdn.com/content/v1/5ec321c2af33de48734cc929/1618497259178-6XJGK9GR6YAVBQL5L519/20140301_Trade-151_012-2.jpg News https://images.squarespace-cdn.com/content/v1/5ec321c2af33de48734cc929/1607694583486-2PQT0LQ193RL7MCB6DX4/20140228_Trade+151_0046.jpg News https://images.squarespace-cdn.com/content/v1/5ec321c2af33de48734cc929/1607694644871-IC85FNH781UNZSZEGHDR/Aro+Ha_0428.jpg News https://images.squarespace-cdn.com/content/v1/67b94584cb4968452d57305e/73f2a731-a348-495c-a3be-60b7c71545dc/Conceivable-Featured-In_Forbes.png News An illustration of a misspelled phrase 'BOLD BOLG' in stylized black text https://images.squarespace-cdn.com/content/v1/67b94584cb4968452d57305e/1744230065287-URSF3VTA39VCYF4LGUNG/Conceivable-1.jpg News “It was truly a privilege to witness the remarkable innovation taking place at Conceivable Life Sciences." — Carlos Simon, Co- President and Founder, Carlos Foundation for Research in Women' s Health, Founder & Scientific Director of IGENOMIX & 25 yrs. IVIRMA, Scientific Director https://images.squarespace-cdn.com/content/v1/67b94584cb4968452d57305e/88f92257-d4b4-4c76-a240-4411f2259d34/Conceivable-Featured-In_FemTech+Insider.png News Black circular badge with white text that reads "FEMTECH INSIDER". https://images.squarespace-cdn.com/content/v1/67b94584cb4968452d57305e/1744230088071-CAT14D1OL4M2SA160H0R/Conceivable-2.jpg News "Our Maven Clinic executive team got a glimpse into the near-future. We witnessed the world's first fully-automated embryology lab. Today embryology is an artisanal craft that is dependent on expert but fallible human beings. Tomorrow, automation will standardize quality, decrease costs, democratize access to fertility assistance for people in need.” — Neel Shaw, Chief Medical Officer, Maven Clinic https://images.squarespace-cdn.com/content/v1/67b94584cb4968452d57305e/42d4ba47-ba75-4f63-a71e-4bc370e223ae/Conceivable-Featured-In_Fortune.png News Black and white drawing of a basketball player jumping to dunk or shoot, with a basketball in hand and an audience in the background. https://images.squarespace-cdn.com/content/v1/67b94584cb4968452d57305e/1744230111260-64XT61VFFDDMGZTHUQY2/Conceivable-3.jpg News "I had the privilege of witnessing Conceivable Life Sciences in action at Hope IVF and I left feeling nothing short of inspired. Seeing this groundbreaking technology firsthand—and meeting the visionary team behind it—was a moment of true excitement for the future of reproductive care. I cannot wait to bring the benefits of this innovation to our patients. " — Cristina Hickman, Founder and Managing Director Avenues https://images.squarespace-cdn.com/content/v1/67b94584cb4968452d57305e/77ff4421-a4bb-438c-8b94-3f6026b94223/Conceivable-Featured-In_The-Economist.png News Close-up of a yellow and black monarch butterfly perched on a green leaf https://images.squarespace-cdn.com/content/v1/67b94584cb4968452d57305e/1744230130582-Y1XZWTUUPMBH7W0S281C/Conceivable-4.jpg News “We are very excited to see what lives will be changed by this fantastic technology and group of people.” —Dr. Angie Beltsos, Founder, CEO Vios Fertility Institute https://images.squarespace-cdn.com/content/v1/67b94584cb4968452d57305e/053dc6a6-b22c-44c2-85f6-6d34efff8fe5/Conceivable-Featured-In_Business-Insider.png News Black text that says 'BUSINESS INSIDER' on a transparent background https://images.squarespace-cdn.com/content/v1/67b94584cb4968452d57305e/1744230143889-E99NPHMGG1CD3XO9RKN1/Conceivable-5.jpg News “This is the biggest thing happening in IVF right now, by far”. — Griffin Jones, Founder, Owner, Fertility Bridge https://images.squarespace-cdn.com/content/v1/67b94584cb4968452d57305e/873c022c-0309-4eb2-98d0-ff2999f79a17/Conceivable-Featured-In.png News A close-up of two black and white cats sitting together on a metal surface with their heads touching. https://images.squarespace-cdn.com/content/v1/67b94584cb4968452d57305e/1744644910134-2OSV9FDI22978P9K3BNG/Conceivable-News.jpg News "Lab automation is a transformative breakthrough that will help us accelerate access to treatment and standardize over two hundred critical variables." 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